Cardiac electrophysiologist and inventor at the intersection of medicine, engineering, and artificial intelligence. Pioneering AI-enabled diagnostics, implantable devices, and the future of preventive cardiology.
Dr. Paul A. Friedman is a Professor of Medicine at Mayo Clinic College of Medicine and Science, holding the Betty Knight Scripps–George M. Gura, Jr., M.D. Professorship in Cardiovascular Medicine. He is a dual-trained physician-engineer whose work spans cardiac electrophysiology, artificial intelligence, and medical device innovation.
With over 30 years of professional experience, Dr. Friedman has served as Director of the Cardiac Implantable Device Lab at Mayo Clinic and has been the driving force behind multiple generations of implantable cardioverter-defibrillators, pacing systems, and AI-powered diagnostics now used in clinical practice worldwide.
A prolific inventor recognized as a Minnesota Top Inventor and recipient of the 2022 Mayo Clinic Distinguished Inventor Award, he holds over 40 biomedical patents spanning medical devices, signal processing, remote monitoring, and AI applications in cardiology.
Education & Training
Developing and validating AI algorithms that detect cardiac dysfunction, atrial fibrillation, amyloidosis, and diastolic dysfunction directly from 12-lead ECGs — enabling screening at population scale.
Board-certified clinical cardiac electrophysiologist specializing in ablation, arrhythmia management, and nonpharmacologic therapies for complex rhythm disorders.
Pioneering work in ICD therapy, cardiac resynchronization, and next-generation extravascular ICD systems. Innovating remote monitoring platforms for proactive cardiac care.
Prospective research on smartwatch-enabled detection of left ventricular dysfunction, bringing passive cardiac surveillance to consumer-grade wearable technology.
Deep expertise in AF detection, characterization, and management — spanning clinical care, device-based therapy, ablation, and AI-powered screening strategies.
Integrating AI-enabled risk models into preventive medicine visits to surface subclinical cardiac disease before symptoms emerge, fundamentally shifting the care paradigm.
Dr. Friedman holds over 40 issued biomedical patents spanning the full spectrum of cardiovascular medicine and medical device innovation.
Mayo Clinic · Department of Cardiovascular Medicine · Rochester, Minnesota